- Preparing for IRB Reliance as the Lead Investigator (~2 mins)
- Using the Study Registration Process (~2 mins)
- Serving as the Lead Investigator (~2 mins)
- Serving as the Relying Site Investigator (~2 mins)
study team benefits of single IRB review for multi-site studies
- Reduce time for IRB approval
- Increase consistency in IRB determinations
additional investigator benefits from IRBchoice
- Provides access to growing national network of member institutions
- Generates study-specific IRB submission instructions
- Offers single point of entry to initiate the reliance process
- Sends automated notifications to facilitate communication across sites
The investigator/study team work flow will depend on whether your institution is the Lead IRB + what model is being used.
If your IRB is the Lead IRB:
- you only have to submit and report to your IRB.
- using the ceded model, your IRB may ask you to submit information on behalf of the other sites in the study (relying sites). a coordinating center may also be in charge of submitting documents for relying sites.
- using the shared model, you may have to disseminate your IRB-approved consent form to other sites in the study (relying sites) to use in their submission to their IRB. a coordinating center may also be in charge of submitting documents for relying sites.
If your IRB is the Relying Site:
- using the ceded model, you may have submission responsibilities to the Lead IRB as well as your local IRB.
- using the shared model, you do not have to submit anything to the Lead IRB, but you will have to communicate with your local IRB to determine what to submit for review (e.g., is a short form IRB application available?)